UCL Cancer Institute Medical Genomics Group Research Data

UCL Cancer Institute Medical Genomics Research Data, including: 

• early Human Epigenome Project (HEP) files (hep_data.zip)
• MeDUSA (Methylated DNA Utility for Sequence Analysis) MeDIP-seq computational analysis pipeline files (medusa.zip)
• human CpG Beacons (human-specific CpG dinucleotides, humanCpGBeacons.zip) 
• tri Primate Methylome files (triPrimateMethylome.zip)
• Medical Genomics web files (tdg_web.zip)

A tarball with all files is included (cancer.ucl.ac.uk.tar.gz)

References

• MeDUSA (Methylated DNA Utility for Sequence Analysis) MeDIP-seq computational analysis pipeline: 
  • Wilson GA, Dhami P, Feber A, Cortázar D, Suzuki Y, Schulz R, Schär P, Beck S. Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers. Gigascience. 2012 Jul 12;1(1):3. doi: 10.1186/2047-217X-1-3. PMID: 23587164; PMCID: PMC3617451.
• human CpG Beacons (human-specific CpG dinucleotides, humanCpGBeacons.zip):
  • Bell CG, Wilson GA, Butcher LM, Roos C, Walter L, Beck S. Human-specific CpG "beacons" identify loci associated with human-specific traits and disease. Epigenetics. 2012 Oct;7(10):1188-99. doi: 10.4161/epi.22127. Epub 2012 Sep 11. PMID: 22968434; PMCID: PMC3469460.
• Human Epigenome Project (HEP):
  • Beck S, Olek A, Walter J. From genomics to epigenomics: a loftier view of life. Nat Biotechnol. 1999 Dec;17(12):1144. doi: 10.1038/70651. PMID: 10585673.
• tri Primate Methylome files (triPrimateMethylome.zip):
  • Wilson GA, Butcher LM, Foster HR, Feber A, Roos C, Walter L, Woszczek G, Beck S, Bell CG. Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases. Genome Med. 2014 Mar 5;6(3):19. doi: 10.1186/gm536. PMID: 24598577; PMCID: PMC4062055.